Colorado Multiple Institutional Review Board

UCD Index

Where to Begin as a Researcher?

Please see the "How To's of COMIRB" page for instructions on submitting many of the documents and forms required for Human Subject Research.

See the Policy & Procedures page for instructions detailing investigator responsibilities and the complete COMIRB Policy and Procedures document

What if I want to enroll in a Study?

Please see the Research Subject Information page if you are intested in being a participant in a study.

An Introduction for New Researchers:

Are you doing human subject research?
	IRB review is only required when you are doing human subject research
	To help you decide, view our Decision Tree
	Other Resources: OHRP Decision tree to help determine if your project is human subject research
	If you are not doing human subject research, but you are still requesting an IRB review determination. You may submit at Exempt application for “Not Human Subject Research Determination”

What type of IRB review do you need?
	There are three types of IRB review levels: Exempt Review, Expedited Review, and Full Board Review.
	Exempt Review- for studies that may meet the criteria established by federal regulations There are six categories of research that are exempt Other resources: the OHRP Decision trees to help determine if your project is eligible for exempt review: The COMIRB/HSRC instructions for submitting an exempt review can be found here.
	Expedited Review- for studies involving certain types of minimal risk There are eight categories of research that may be expedited, with some limitations by HSRC/COMIRB Other resources: the OHRP Decision trees to help determine if your project is eligible for expedited review: The COMIRB/HSRC instructions for submitting an expedited review can be found here.
	Full Board Review - for studies involving more than minimal risk or is otherwise not eligible for exempt/expedited review All other research must be reviewed by a fully convened panel The instructions for submitting a full board review can be found here.

How do you notify the IRB about new information on a protocol?
	To change the COMIRB application and/or protocol - submit an Amendment form To change or submit other study documents - submit an Update form To submit a continuing review To close a study Other notifications - please submit general correspondence to COMIRB that references the study title, protocol number, and principal investigator
	For HSRC - To change the HSRC application, protocol, or other study documents- submit an Amendment/Update form To submit a continuing review To close a study Other notifications - please submit general correspondence to HSRC that references the study title, protocol number, and principal investigator

Still not sure how to submit to COMIRB?
	Contact the COMIRB team for more information